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Lennox-Gastaut Syndrome


ICD-10: G40.4

ORPHA: 2382

General information

Estimated occurrence
15:100,000 live births.
Lennox-Gastaut is a difficult-to-treat type of epilepsy that can be due to genetic factors, abnormalities, infections, tumours or skull injuries.
General symptoms
The diagnosis is made based on a typical EEG pattern. Lennox-Gastaut syndrome involves severe epilepsy with various types of seizures. The seizures’ character is determined by where in the brain the discharge appears. Developmental disorders, behavioural problems and language disorders are common, as are motoric difficulties.

Orofacial/odontological symptoms

Dental damage can occur due to falls and biting injuries. Some epilepsy medication can affect gums, making them thicker and more likely to bleed. Medication can also lead to dry mouth. Many sufferers have oral motor dysfunction, often leading to difficulties eating and speaking as well as saliva leakage.

Advice on follow-up and treatment

  • Early contact with dental services for intensified prophylactic care and oral hygiene information is essential in cases of difficulty with managing dental treatment and tooth brushing.
  • Oral motor training and stimulation may be appropriate in cases of eating difficulties, speaking difficulties and reduced saliva control.
  • Speech, language and communication training is often warranted.
  • Feeding and swallowing difficulties are investigated and treated by a specialist team at the hospital or multidisciplinary treatment centre.


Updated: 2019-11-12 14:53